And They're All Really Sound Reasons

5 Reasons Why You Can't Put An F1 Engine In A Road Car

It would be an incredible feat of engineering to shoehorn an F1 engine into a road car, but the logistics behind this form of engine swap just wouldn't match up

1. They are notoriously difficult to start
2. They're not cheap
3. Cooling
4. That fuel bill though
5. The lifespan is tiny

(CarThrottle.com)